Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

The so-called IP-BOX will work on iPhones running iOS 7 and older. It takes 6 seconds to 17 hours hours to crack the four-digit passcode. The Daily Mail purchased the device and cracked the code on an Apple iPhone 5c in 6 hours. A version that will work on iPhones running iOS 9 will be available later this month.
GMAT平均分:700分
Hannah Kuchler is San Francisco correspondent
众所周知中国一直在雄心勃勃地推进航天商业化,最近中国取得的进展正在将这一梦想转为现实。
50个最优秀的“无工作经验要求”项目的所有毕业生中,三分之一以上毕业于英国的商学院。英国的商学院还吸引了近一半的女学生以及近一半的国际学生。实际上,2014年一个英国“无工作经验要求”金融硕士项目招收的学生中,有94%来自海外。这些学生当中约有85%来自欧洲经济区(European Economic Area)以外,55%来自中国内地。
A hero is one that doesn't want to bea hero. A hero is a one with all the possibility to make the choice but takethe responsibility of the moment. And it's really something hero has got to do.For example, in 9/11 some of the plane's passengers fought with the terrorists.In Fukushima's radiation leak, some people went and tried to fix the nuclearplant and died. But they have to do it. They are heroes. They don't try to beheroes. They take responsibility and try to do what is right.
Succeeding as an entrepreneur takes hard work and persistence because, unfortunately, there is no business-startup fairy who magically bestows success on small businesses and their owners.
adj. 泰然自若的,镇定的;摆好姿势不动的,静止的;平
同时,美国Rapper歌手Eminem被证明是“复出王”,摘得最佳Hip Hop歌手奖。”The Lose Yourself ”的创作者与Hip Hop的新面孔相互竞争,包括Drake, Future, Kendrick Lamar and Post Malone。
On the subject of #MeToo, she said: 'I just think they're douche bags. They're not champions. I just think they're losers. I don't like them.
曼谷重回首位,而付出代价的是伦敦。伦敦在连续两年占据榜首后,与其亚洲对手城市交换了位置。
It was not an auspicious start to the new year for bitcoin investors.
Only the US-based MIT Sloan School of Management, in fifth place, prevented French institutions from sweeping the top five positions.
不过,行业、企业间的高管薪酬差距明显。
劳瑞斯蒂尔
Simply bend one end of the product around yourself or the back of your seat and bend the other end into a secure position for your head. You can even use the hand to hold your device for movie time.
planet
Add your scores for 10 to 14 to find out how you score on the Social Inhibition scale.
['k?mpleks]
"Poverty has stunted further growth in Internet users, which has kept the Net user population to around 50 percent," Li said.
v. 商讨,向 ... 请教,查阅
n. 声明,陈述
And a few stopped to change a tire for an elderly French couple.
单词regulate 联想记忆:
“Nick is an exceptional product thinker,” Adam Cahan, Yahoo’s senior vice-president of mobile and emerging products, said. “He does represent a generational shift in the kinds of things he is thinking about and what it means to be truly mobile. That generation is not just mobile-first, they are mobile only. That’s a different point of view.”


不断上演的进球大战正是本届世界杯精彩绝伦之处。
So too would be concluding the EU’s own (re)negotiation of its existing trade agreement with Mexico. And there is a good chance Brussels could beat Donald Trump to the finish line on a deal with Mexico.
7、Bad body language habits


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

它被广泛误解为一部关于小说家大卫·福斯特·华莱士(David Foster Wallace)的传记电影,其实庞索特的这部影片是一部关于新闻的坏方法的喜剧,以及对文学名誉机制充满了解的辛酸讽刺。杰西·艾森伯格(Jesse Eisenberg)与杰森·西格尔(Jason Segel)使用“男人老友电影”(buddy movie)的传统方式,完美地呈现出一个新的子类:亦敌亦友电影。
Song “Beautiful China”(Sha Baoliang and Xu Qianya)
It was there in Rossella Jardini’s Moschino, from the bows and bouffants of spring-summer 2009 to the Mary Quant-inspired spring 2013 collection.
立场:承诺聘用老兵

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

主流网络游戏仍然是大型多人在线角色扮演游戏 (MMORPG)。报告说,今年10月,中国最热门的10款网络游戏中有6款都属于大型多人在线角色扮演游戏。动视暴雪(Activision Blizzard)开发的《魔兽世界》(World of Warcraft)在注册用户和最高同时在线人数方面仍然排名榜首。但报告指出,目前围绕着这款游戏大陆运营权的政府监管纷争可能会给《魔兽世界》带来负面影响。网易公司目前持有《魔兽世界》的中国大陆独家运营权。

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

在英国,今年可能是大型咨询公司正式进入法律市场的一年吗?其他的“另类业务结构”——或者说按照“乐购法”(Tesco law)成立的律所——将通过提供固定费用服务、把业务外包给松散的律师网络,或者推出法律聊天机器人提供即时而实惠的建议,而终于立足消费者市场吗?为了普通公民的利益,得有人突破这个领域。
During the same period, Braziland Russia slashed their holdings to USD 261.7 billion and USD 108.9 billion,respectively.

上榜的12所美国学院平均而言是性别比例最为平衡的,女性学员比例为48%。
他仅面临这几个障碍:他的手下、国会里的共和党人以及总统行政权的限度。而这几个障碍都非常有分量。他竞选时声称要对中国货物征收45%关税的承诺,已经变成对中国知识产权做法展开调查。
公牛队当家球星罗斯的这两张照片就跟在照镜子一样,可能是因为照片中的罗斯还处于2006年的高中时代,也不过是六年前。
He then proceeded to ram the violin through the canvas.
尽管销量大幅增长让人欢欣雀跃,但它并不是汽车业今年最重大的新闻。底特律先是因为通用汽车公司(General Motors)提拔玛丽?芭拉出任汽车业首位女性首席执行官而欢欣鼓舞;紧接着,福特汽车(Ford)首席执行官艾伦?穆拉利在重回波音公司还是加入微软公司(Microsoft)两者间犹豫不决之际,它又紧张得大气都不敢喘。传统的三巨头抱怨现有产能已挖掘到极限,开始制订扩张和聘用新人的计划。特斯拉公司(Tesla)让电动汽车的销量火了一把,而且不肯按行规出牌;而同时谷歌公司(Google)则在自动汽车研制上一马当先。
一个问题接着一个问题,从伊朗制裁到从阿富汗撤军,他的位置和政府态度之间的差别不大,但罗姆尼坚持他将更有效地加强美国的力量。

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


职场人生活状态报告:逃离一线城市首因是房价高


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


Saif held the highest position among the five ranked Chinese schools, just ahead of Guanghua School of Management and Tsinghua University School of Economics and Management, 17th and 18th respectively.
排名第55位的爱丁堡大学商学院重获两年前的排名。该商学院去年在未能进入管理硕士排行榜之后排名大跌。布拉德福德大学管理学院由于首次进入EMBA百强榜单而录得史上最大进步。
Google has brought out the list of the most searched topics in its search engine this year.
里尔宁援引了荷兰经济政策分析局(CPB Netherlands Bureau for Economic Policy Analysis)的最新数据,数据显示,9月至10月经季节性调整的全球贸易量下降了1.1%,他表示,去年将被证明是世界贸易自2009年以来表现最糟糕的一年。
5.射击类比赛项目
Another fashion high-flyer making her mark on the first day of the world-famous festival was Winnie Harlow. The Canadian model - who has the skin condition vitiligo - nearly took Emily's crown, as she made a play for the attention with her elegant belle of the ball outfit.
Under the Skin is just so visually free and uninhibited that there is an intense dark, destructive sexiness in everything about it – quite apart from the hilarious, bizarre, mesmeric eroticism of the film itself. It is a work of subcutaneous potency. It gets under your skin.
McDonald's (MCD, Fortune 500), the all-American fast food Mecca, announced it would put $20 billion towards share repurchases and dividends Thursday, jumping on board the buyback trend that has boomed over the past 18 months.
China must walk a narrow line at a time when its outgoing leadership is reluctant to take any far-sighted decisions.
凭借这场胜利,金州勇士队追平了由1957-1958赛季的波士顿凯尔特人队创造的卫冕冠军赛季开局14连胜纪录。而勇士队也是成为在NBA历史上,仅有的五只以14胜0负开局的球队。接下来,他们将会作客丹佛,力争在周日将纪录继续保持下去。

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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每个伟大的侦探都需要专属于自己的经典故事。对于福尔摩斯而言,这个故事是《巴斯克维尔的猎犬》。对于阿加莎?克里斯蒂笔下龟毛的比利时侦探赫克尔?波洛而言,这个故事是《东方快车谋杀案》——故事讲述了一个嗜血的恶棍在驶向巴尔干半岛的列车上杀死了一个有钱的商人。真相果真是如此吗?西德尼?吕美特曾在1974年将该故事拍成了一部备受喜爱的电影,强大的演员阵容包括肖恩?康纳利、英格丽?褒曼和阿尔伯特?芬尼(饰演侦探波洛)。如今肯尼思?布拉纳自己戴上了侦探波洛的大胡子,披挂上阵,同时又担当幕后导演。这部新版电影的演员有约翰尼?德普、黛西?雷德利、米歇尔?菲佛、佩内洛佩?克鲁斯和朱迪?丹奇。这个故事还能挖掘出什么新内容呢?也许会有。不过,即使没有,阿婆的粉丝也肯定会去看。这部电影将于11月3日在英国上映,11月10日在美国、中国和土耳其上映,11月30日在中国香港和新加坡上映。(资料来源:二十世纪福克斯电影公司)
Battle of the box office 电影贺岁档引发票房PK
*喜剧类最佳客串男演员:彼得?斯科拉里(Peter Scolari),《都市女孩》(Girls)
So ladies, we have been warned. What would your response be?

Of the 27 provincial-level regions that outpaced the country's 6.7% GDP growth in 2016, only three regions - Chongqing, Guizhou and Tibet - achieved double-digit growth.

  • Only the first three authors are listed, followed by "et al."
  • 楼市降温 2017年住宅成交量有望回到2015年水平
  • 关注中介乱象:上了中介当 维权咋这么难?


"Nobody can stop it. I will keep sending leaflets into North Korea at the risk of my life," Park said, adding he has always prepared to face down the North's threats.
Gitanjali Rao was selected from 10 finalists who had spent three months collaborating with scientists to develop their ideas.

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