Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

4. We can’t go into detail on this matter.
我们第一次看到安娜·莫拉莱斯(Anna Morales,杰西卡·查斯坦[Jessica Chastain]饰)的头发是在《至暴之年》(A Most Violent Year)的片头字幕里。她正对着镜子化妆。
2015年首个周末,全球第二大比特币交易所——位于斯洛文尼亚的Bitstamp遭到黑客袭击,丢失了价值约500万美元的比特币。科技媒体很快指出,此事令数字货币比特币2015年开局不利,财经新闻网站QUARTZ曾称比特币为“2014年最糟糕的投资”。纵观该数字货币2014年1月1日至2015年1月1日的表现,QUARTZ此言非虚:2014年底,比特币的价值仅为同年年初的39%。
n. 饰带,花边,缎带
10.谎言和誓言的区别在于,一个是听的人当真了,一个是说的人当真了。
2. Shanghai, China-The enormous metropolis of Shanghai—China's most populous city—has an historic urban core which sits alongside its status as a contemporary, global financial hub.
Pork prices, which are heavily weighted in the food-focused basket of goods used to calculate consumer inflation, rose 4.8 per cent.
赢家:雷霆
在排名靠前的学校中,英国华威商学院(Warwick Business School)排名提升最大,从第16位提升至第9名。整体而言,上海交通大学(Shanghai JiaoTong University)的上海高级金融学院(Shanghai Advanced Institute of Finance)排名提升最大,从第28位提升至第14位。
v. 燃烧,面红,爆发
美国太空探索技术公司在航天器充分回收方面取得重大进展
A Method to the Madness
上海实施新措施一年以来,受理外籍人士及其家属永久居留申请同比增长6倍。
1号 what the fuck: “职场辣妈”的新境界
这种成功的感觉本身也可以带来一种身份认同。
10. The 2012 Ig Nobel Prize in Medicine
2016年,9个省级地区的GDP超过3万亿元,比上一年增加3个;25个省级地区的GDP突破1万亿元,与上一年持平。
Traffic was halted along Interstate 68 in Frostburg, Maryland on Tuesday. Wet snow and high winds spinning off the edge of superstorm Sandy spread blizzard conditions over parts of West Virginia and neighboring Appalachian states.
1. World Health Organisation declares a public emergency of international concern over Zika
31岁的扎克伯格去年的表现力压群豪,个人资产上涨了112亿美元,从去年的第十六位跃升至今年的第六位。这是他和杰夫·贝佐斯首次进入福布斯年度排名榜单前十位。
“The US economy is likely to grow by 3 per cent plus this year as well as next year.
Stand: Wal-Mart U.S. President and CEO Bill Simon pledged to hire veterans
愿一切最美好的祝福都能用这张贺卡表达,真诚地祝你幸福、快乐、成功!
Hurun Chairman Rupert Hoogewerf said: "Those entrepreneurs should be called 'super wealth creators' instead of simply 'rich people', which could highlight their contribution to China's society and economy."
Foreign robot makers sold 103,191 robots to China in 2017, up 71.9% from a year earlier.


[s?'plai]
"Overall this ranking of Asia's best 300 universities proves what a dynamic, diverse and competitive higher education region the continent is becoming -- and China is a key part of that development," said Baty.
The number of inbound travelers to Beijing grew after the city hosted the 2008 Olympics until 2012, when it saw a 3.8% decline, followed by the further drop last year.


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

And now for the companies that lost the most love ...
Mr Hoogewerf said that Mr Wang delisted his group’s property arm from the Hong Kong stock exchange this year in the hope of realising a richer valuation for it on the Shanghai or Shenzhen bourse.
The show is iconic among those who grew up in the 1990s because it explores core themes like friendship, struggling to survive in a big city, and finding independence and identity, all of which are still relevant to young audiences today.
A sequel to X Men: Days of Future Past, the latest instalment in the X Men series will see them fight the villain Apocalypse. The movie might see the return of a few older characters and a lot of new ones. We don't really know anymore than that, but it is going to be one amazing film, that's for sure.

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

1. The remote control belongs to me for the whole month.

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

Harvard topped the league table, followed by Massachusetts Institute of Technology and Stanford University.
Dachis says: Starbucks is a perennial top-performer in social and 2012 was no exception. The company’s social savvy earned it 19 million new fans and followers in 2012 and its push into at-home and on-the-go products gave all those people something fun to talk about.

伦敦——在20世纪70年代,英国喜剧演员汤米·库珀(Tommy Cooper)讲过这样一个笑话:他在阁楼里发现一把小提琴和一幅画,让拍卖公司估价。拍卖公司说,好消息是它们分别出自斯特拉迪瓦里(Stradivarius)和伦勃朗(Rembrandt)之手。坏消息是那幅画是斯特拉迪瓦里画的,小提琴是伦勃朗做的。
4、慧眼识香。邦德眼光敏锐,能辨认出孰敌孰友。这种品质常见于性开放者。007很容易识出对他有意的女人,有科学证明,帅哥往往擅长于此。
The book — published by Basic Books and Oneworld Publications — won out against a strong shortlist dominated by books on technology.
质量强国、制造强国
中国信息通信研究院的报告称,2016年国产手机出货量达4.98亿部,占国内手机总出货量的88.9%。
Fuel for this latest burst of Tesla mania came from none other than Chairman and CEO Elon Musk in comments he made during an analyst call on July 31. The big news wasn’t that Tesla reported higher production for the second quarter and beat earnings estimates again.

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


楼市局部现回暖 市场分化仍持续


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


我们在中高速行进当中也会系紧安全带,不会让风险“急性发作”,更不会发生区域性或者系统性的风险。
达成一个全球性气候协议的下一次大尝试,将是在来自世界各地的谈判代表今年12月聚集巴黎的时候。气候变化问题的政治活动人士上周五不失时机地引用2014年的温度记录为证,表明采取强有力行动的必要性。
SIZE: 5,003 square feet total
7.思想控制仿生腿
7. 2012年搞笑诺贝尔奖之物理学奖
支持:该片在多伦多国际电影节上获得人民选择奖,这个奖项通常是一个重要的风向标。
北京市旅游发展委员会指出,污染问题是中国在吸引外国游客入境旅游的过程中面临的又一障碍。
Makers of processed food, soda and fast food see markets in the developing world as their greatest growth opportunities. At the same time, obesity rates and weight-related illnesses are on the rise in developing countries. An ongoing series of articles examined the interaction of these two trends, starting with cases in Brazil, Ghana and Colombia. Taken together, these stories reveal “a new global food order, and a new health crisis.”
Writing for a Comedy Series: Aziz Ansari and Alan Yang, “Master of None” (“Parents”)
The 16-year-old surnamed Zhou on April 24 poured pesticide into the water dispenser in the classroom, apparently in an act of revenge against classmates who disturbed the class and affected Zhou's studies, the Chongqing Morning Post said.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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吉密欧(Jamil Anderlini)
葡萄牙诺瓦商业与经济学院(Nova School of Business and Economics)巩固了去年的强劲表现,排名进一步攀升14个位置,排在了第17位。
The rise of ephemeral social networks
祝新年快乐,并致以良好的祝福。

adj. 推测的,推理的,思索的,投机的

  • Only the first three authors are listed, followed by "et al."
  • 住建部:把稳地价稳房价稳预期的责任落到实处 补齐租赁住房短板
  • 海淀共有产权房明起申购!均价3万五


对于在泥潭里挣扎的球队,有一样建队过程中关键的东西一直诱惑着他们,那就是建队计划。
答:和青木桑一起处理分镜真的是一件很快乐的事呢。有一种“队伍里会有青木桑是毫无疑问的吧“这样的感觉。有了他,相信动画的表现就不会有问题了呢。

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